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We are a San Diego based biotech seeking a Scientist, Assay Development (PCR Expert)
We have an immediate opportunity for a PCR expert in the Assay Development group for PCR assay development and validation for GLP and Clinical use. This person will be responsible to independently develop, qualify and validate in house and customer real-time PCR and multiplex PCR assays to measure gene expression, copy number, genotype, translocations and other molecular characteristics of RNA or DNA, which will be used in clinical and pre-clinical quantitative and qualatitative biomarker and companion diagnostic studies. He/she will independently perform assay design, establish assay development and validation protocol and carry out experiments; be responsible for accurate testing, documentation of results, and evaluation and analysis of data; provides technical and theoretical support to testing staff within area of specialty; researches and implements new methods and technologies to enhance operations; suggests improvements to existing methods and procedures; offers novel approaches and troubleshooting to solve complex technical problems; trains staff in scientific method and testing technologies; employs high level technical expertise to develop new techniques and creatively solve problems; reliably writes and executes well defined SOPs; interacts with clients to understand the project scope and prepares complex and detailed reports; complete other duties as assigned by supervisor.
Requirements: A bachelor degree with 12 years PCR/molecular biology related industrial experience, a master degree with 9 years experience or a Ph.D. degree with 3 years experience. Detailed knowledge of PCR assay development and validation at clinical level and a minimum of 3 years proven experience in PCR assay development and validation is required. Familiarity with regulatory guidance on analytical testing and clinical molecular biology lab working experience is highly desired. Experience with assay development using FFPE fixed tissue samples is a plus. Demonstrated ability to understand and apply complex technical concepts to assay development methodology; detail oriented and strong written and verbal communication skills; ability to work independently, within prescribed guidelines, and as a team member; ability to follow detailed directions in a laboratory environment.
- Location: San Diego
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